Pleural Mesothelioma

Nearly 75 percent of mesotheliomas are initiated in the chest and are called pleural mesotheliomas. Pleural mesothelioma is the most common form of this devastating disease. This occurs when asbestos fibers enter the pleura, which is the membrane that covers the lungs, and results in the formation of malignant cells. The people most at risk of developing this rare form of cancer are construction workers who have been exposed to asbestos fibers for extended periods of time, their families, who are exposed to the asbestos fibers that collect on the clothes of the workers, and people who live or work in buildings that are insulated with asbestos material.
The risk of developing malignant pleural mesothelioma depends on several factors, such as the length of time the person has been exposed, and the nature of the asbestos fibers involved as well as the different kinds of industries. Other factors can also contribute to onset of pleural mesothelioma.
The symptoms at the initial stage can resemble that of pneumonia. When malignant mesothelioma originates in the pleural cavity, the first symptom may be a mild pain in the chest or back. When malignant pleural mesothelioma spreads, organs and tissues in the immediate area can be affected. It grows into the chest wall, muscles and ribs. The pain changes from mild, general and episodic to severe, localized and chronic as the disease progresses. Severe pain may not respond to oral doses, intravenous infusions, or intramuscular injections of analgesics or narcotics.
There are at least two other forms of mesothelioma, but pleural mesothelioma responds best to treatment. Unfortunately, the fatality rate remains high. However, extensive research is going on to alleviate the pain of mesothelioma sufferers, develop a vaccine, and treat the progression of the cancer.

Malignant Pleural Mesothelioma

Malignant pleural mesothelioma is a cancer of the thin layer of tissue that lines the chest and lungs. It is a rare form of cancer that is mostly associated with exposure to asbestos. Malignant pleural mesothelioma is a fast-moving cancer with a median survival time of between one and two years.
The majority of mesotheliomas are associated with asbestos exposure. Asbestos was used widely in the United States for insulation, and while awareness of its harmful effects is increasing, asbestos can still be found in older buildings. People who work in industries using asbestos in some form, such as insulation manufacturers, insulation workers, and ship builders, may be at increased risk to develop mesotheliomas. The time between exposure and development of a cancer may be decades, which is why it is usually diagnosed in older people. More men than women get this type of cancer. Close contacts of people who have been exposed to asbestos, such as family members, may also be at risk.
Some symptoms of this cancer are increasing breathlessness, pain in the chest or under the ribcage, an abdominal lump or swelling, fever and unexplained weight loss. Imaging tests like a CT scan may show a collection of fluid in the pleural cavity of the chest. Pleural tissue and fluid is also tested to detect cancerous cells and certain chemicals that can rule out a diagnosis of pleural mesothelioma.
Depending on the extent of spread of cancer, malignant pleural mesotheliomas are conventionally treated with some combination of chemotherapy, radiotherapy and surgery to remove as much of the cancer as possible. Aggressive treatment strategies are the norm, though the exact treatment depends on how far the cancer has spread. A number of experimental treatments are currently being evaluated in clinical trials.

Asbestos - The Difference Between Lung Cancer and Mesothelioma

Asbestos has been shown to cause a host of health problems for those who inhale it. As such, it starts off as a respiratory disease. Unfortunately, it can develop well beyond that. This evolution has caused a massive amount of confusion to the point that two results, Mesothelioma and lung cancer, are often used interchangeably when they should not be.
Asbestos exposure can often lead to cancer in the person exposed if the fibers of the mineral in question are breathed into the lungs. Any form of cancer is simply bad news. That being said, there are different types and each comes with its own issues, treatments and potential outcomes. With asbestos exposure, the two most common forms of cancer are Mesothelioma and lung cancer. They are distinct health problems. Let's take a closer look.
Lung cancer obviously impacts the condition of your lungs. Lungs are the biomechanism we use when breathing. They introduce oxygen into our body and expel carbon dioxide and other minor gases like nitrogen. Breathing in air from the environment can be hazardous. In the case of asbestos, we can breathe in tiny fibers of minerals in asbestos forms. Once in our lungs, they are very hard to get out. Slowly, they can cause damage to the structure of the lung material. Scarring, known as asbestosis, and tumors can occur. The tumors can grow and are known as lung cancer. There are various forms of lung cancer, and that discussion is beyond the scope of this article.
Mesothelioma is often talked about as though it is a form of lung cancer. It is not. To understand this form of cancer, one has to first understand what the mesothelium is. The mesothelium is with us from birth. It is a layer of cells that lines the internal organs and areas of the body. It lines the lungs. It lines the abdomen. It lines areas of the heart. The purpose of the mesothelium is much like oil in a car engine - it acts as a lubricating surface that allows the organs in the body to move without friction. Without the mesothelium, bending over would be difficult and probably a very painful proposition.
Mesothelioma is a cancer that occurs in this lining. It is caused by asbestos being inhaled into the lungs. From their, the asbestos fibers are absorbed into the body. How exactly they get into the mesothelium is unknown, but they clearly due. Mesothelioma can spread throughout the entire body core or remain in a particular area. If caught very early, treatment options exist. If caught late, it is rarely survived.
So, how do Mesothelioma and lung cancer get confused when it comes to asbestos exposure? Well, Mesothelioma often occurs in the mesothelium lining around the lungs. Although not technically lung cancer, once can see how the two would get confused. Still, it is important to remember that each is unique and calls for different treatments.